The Houston Astros will open the 2025 season on March 27 with an Opening Day matchup with the New York Mets. The Astros have never played an Opening Day game against the Mets in it’s 63-year history, which is a franchise that entered the Major Leagues in the same year as the Astros franchise (1962). This also marks the first time in club history that the Astros have played an Opening Day game against an Interleague opponent.
The opening homestand is a six-game set, featuring a three-game series with the Mets (March 27-30), which includes an off day after Opening Day, and a three-game series vs. the San Francisco Giants (March 31-April 2). The Astros’ first road trip of the season is a six-game trip, which will take the club through Minnesota (April 3-6) and Seattle (April 7-9). Houston will host 21 different teams at Minute Maid Park in 2025, which includes seven National League clubs and all 14 other American League clubs.
Other notable home series on Houston’s schedule include the Padres (April 18-20), Twins (June 13-15), Cubs (June 27-29), Rangers (July 11-13), Orioles (Aug. 15-17) and two against the Mariners (May 22- 25, Sept. 19-21). The Astros will also host weekday games against the Blue Jays (April 21-23), Phillies (June 24-26), Guardians (July 7-9), Red Sox (Aug. 11-13), Yankees (Sept. 2-4) and Rangers (Sept. 15-17), among others.
The Astros will host holiday matchups next season on Easter Sunday, Mother’s Day, Father’s Day, and Labor Day and will play a huge July 4 matchup against the Dodgers in Los Angeles.
The Astros will travel to Arlington to play the Rangers twice in 2025, for a four-game series from May 15-18 and a three-game series from Sept. 5-7. They will also play the rival Dodgers in Los Angeles from July 4-6 and the Yankees in New York from Aug. 8-10. The Astros will conclude their season with a three-game series against the Angels from Sept. 26-28 in Anaheim.
Head to astros.com for more information about the schedule and tickets.