| 3-5A Week 6 | Scores |
| 10/5 Acadiana (5-0) vs Comeaux (2-3) | Comeaux 31 Acadiana 30 FINAL |
| 10/5 Barbe (4-1) at Sulphur (2-3) | Sulphur 36 Barbe 35 FINAL |
| 10/5 Lafayette (1-4) at New Iberia (1-4) | Lafayette 30 New Iberia 13 FINAL |
| 10/5 Lagrange (0-5) at Sam Houston (5-0) | Sam Houston 38 LaGrange 0 FINAL |
| 4-4A Week 6 | Scores |
| 10/5 Carencro (1-4) at Northside (2-3) | Carencro 49 Northside 8 FINAL |
| 10/5 Rayne (1-4) at Teurlings Catholic (2-3) | Teurlings 40 Rayne 14 FINAL |
| 10/5 St. Thomas More (4-1) at Westgate (3-2) | St. Thomas More 71 Westgate 20 FINAL |
| 5-4A Week 6 | Scores |
| 10/5 Beau Chene (0-5) at Breaux Bridge (3-2) | Breaux Bridge 48 Beau Chene 0 FINAL |
| 10/5 Cecilia (2-3) vs Opelousas (4-1) | Cecilia 34 Opelousas 20 FINAL |
| 10/5 Livonia (4-0) vs St. Martinville (5-0) | St. Martinville 55 Livonia 34 FINAL |
| 5-3A Week 6 | Scores |
| 10/5 Church Point (5-0) vs Northwest (4-1) | Northwest 44 Church Point 28 FINAL |
| 10/5 Crowley (3-2) vs Iota (5-0) | Iota 41 Crowley 20 FINAL |
| 10/5 Eunice (4-1) at Port Barre (2-3) | Eunice 30 Port Barre 0 FINAL |
| 10/4 Mamou (0-5) at Pine Prairie (2-3) | Pine Prairie 43 Mamou 13 FINAL |
| 8-3A Week 6 | Scores |
| 10/5 Abbeville (2-3) vs Kaplan (2-3) | Kaplan 42 Abbeville 30 FINAL |
| 10/4 Berwick (2-3) vs Erath (0-5) | Erath 36 Berwick 14 FINAL |
| 10/5 North Vermillion (3-2) vs Patterson (1-4) | North Vermillion 52 Patterson 28 FINAL |
| 6-2A Week 5 | Scores |
| 10/5 Kinder (3-2) at Notre Dame (5-0) | Notre Dame 49 Kinder 3 FINAL |
| 10/5 Lake Arthur (2-1) at Ville Platte | Lake Arthur 61 Ville Platte 13 FINAL |
| 10/5 Welsh (4-1) at Jennings (3-2) | Jennings 34 Welsh 30 FINAL |
| 7-2A Week 6 | Scores |
| 10/5 Ascension Episcopal (4-1) vs Jeanerette (2-3) | Ascension Episcopal 42 Jeanerette 14 FINAL |
| 10/4 Catholic New Iberia (4-1) at West St. Mary (1-4) | Catholic New Iberia 63 West St. Mary 26 FINAL |
| 10/5 Delcambre (0-5) vs Franklin (2-3) | Franklin 40 Delcambre 16 FINAL |
| 10/5 Loreauville (0-5) vs Catholic Point Coupee (4-1) | Catholic Point Coupee 58 Loreauville 6 FINAL |
| 5-1A Week 6 | Scores |
| 10/5 North Central (1-3) at Slaughter (2-3) | Slaughter 42 North Central 7 FINAL |
| 10/4 Opelousas Catholic (3-2) at Sacred Heart (3-2) | Opelousas Catholic 32 Sacred Heart 0 FINAL |
| 7-1A Week 6 | Scores |
| 10/5 Centerville (4-1) at Gueydan (4-1) | Gueydan 45 Centerville 6 FINAL |
| 10/5 Central Catholic (1-3) vs Highland Baptist (0-5) | Central Catholic 48 Highland Baptist 0 FINAL |
| 10/5 Hanson Memorial (1-4) vs Lafayette Christian (5-0) | Lafayette Christian 76 Hanson Memorial 0 FINAL |
| 10/5 Vermillion Catholic (5-0) at E.D. White (4-2) | Vermillion Catholic 27 E.D. White 20 FINAL |